The aim of this work is to analyze urban development of Mexico City in its broader, macro-regional context which also describes the term megalopolis, and in its narrower, metropolitan sense. Without attempting to reach premature conclusions, we can say that a metropolis like Mexico City is exposed to processes typical of such cities: more and more extensive land use, changes in economic, social and demographic structures, etc. What is more, like other emerging or accelerating processes, also globalization had an important impact on cities, resulting in both positive and negative changes. This work is an attempt to identify and, if possible, to analyze some of these changes in Mexico City.