The article studies determinants influencing the socially-vulnerable population of Ukraine in the period of the Russo-Ukrainian War. The research encompasses three directions: first, the study of the current number of socially vulnerable groups of the population within the boundaries of the Carpathian area; second, the study and analysis of the determinants influencing the number of socially-vulnerable groups of the population; third, the investigation of the degree of the determinants’ impact on the number of the socially-vulnerable population within the Carpathian area. The authors of the work have shaped five groups of determinants influencing socially-vulnerable population, namely national, administrative, economic, demographic, and social ones. The research confirms that before the war started in Ukraine, the number of socially-vulnerable population had been reducing both in the country and within the Carpathian area. In particular, in 2001–2021, the number of vulnerable groups of the population reduced by 23% in Ukraine, in the Chernivtsi region – by 24.5%, in the Ivano-Frankivsk region – by 10%, in the Transcarpathian region – by 8.6%, and in the Lviv region – by 6.1%. The situation has changed since the war started. Based on the conducted calculations, it is determined that the greatest impact on the socially-vulnerable population is created by the national and economic determinants, whilst the smallest one – by the demographic determinants, whereas the last ones depend on the geographic position of the region. It is also confirmed by calculations of the radar of determinants influencing socially-vulnerable population. During the Russo-Ukrainian War, the greatest impact of the determinants on socially-vulnerable population is marked in the Lviv region.