The main aim of the paper is an attempt to assess whether academic cooperation is an important component of a region’s innovation potential. First, a preliminary operationalization of the most important components of innovation potential is presented based on a literature review. The components are then verified using factor analysis which makes it possible to identify the main dimensions of a region’s innovation potential. The results suggest that academic cooperation is a significant component of the potential, given that the indicators that illustrate it are part of the potential’s „academic” dimension (betweenness centrality) and of its „core” dimension nternationalization). However, the paper shows that cooperation is not linked with the “technological” dimension that, at the time of the study, played the central role in shaping European regions’ growth dynamic. The ”core” dimension, on the other hand, comprising e.g. internationalization of academic cooperation, proved to be significant in explaining the growth dynamics of three out of nine subtypes of regions, the “academic-technological” among others. It may mean that foreign academic cooperation is important for the development of the regions that are key for European innovation potential.